Canadian Neonatal Network

Neonatal Outcomes Probability Score (NOPS) calculator on Day 7, Day 14 and Day 28

Day 7, Day 14, Day 28 - Diagnosis/Interventions

Which day model you are interested in understanding that baby is alive on that day
Ventilated >50% of days up to and including day 4 or more days 7 or more days 14 or more days
iNO >50% of days up to and including day 4 or more days 7 or more days 14 or more days
Inotropes On or before Day 7 On or before Day 14 On or before Day 28
Infection (EOS/LOS) On or before Day 7 On or before Day 14 On or before Day 28
NEC stage 2 or 3 On or before Day 7 On or before Day 14 On or before Day 28

Predicted probabilities ( 95% CI )

Outcome Day 7 Day 14 Day 28
Death before discharge 1
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Death before discharge or severe neonatal morbidity 2
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Death before discharge or BPD 3
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Death before discharge or moderate-severe BPD 4
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1.
Death before discharge from tertiary NICU
2.
Severe neonatal morbidity included periventricular leukomalacia (PVL) defined as increased echogenicity in the periventricular white matter of the brain with or without cystic changes following ischemic insult, by de Vries et al; severe retinopathy of prematurity (ROP) defined as stage 3 or higher ROP or treated ROP or NEC stage 2 or 3 if it developed after model prediction day
3.
Bronchopulmonary dysplasia (BPD) is defined as receipt or oxygen or respiratory support at 36 weeks postmenstrual age or at discharge from level 3 NICU
4.
Moderate to Severe bronchopulmonary dysplasia is defined as receipt of invasive or non-invasive positive pressure ventilation or nasal cannula oxygen of >100 cc/minute (100% oxygen) or nasal cannula delivered blended air and oxygen >21% minute of >1.5L/min at 36 weeks post menstrual age or at discharge from level 3 NICU